There is a growing need to develop novel therapeutics for targeted treatment of cancer.The prerequisite to success is the knowledge about which types of molecular alterations are predominantly driving tumorigenesis.To shed light onto this subject, we have utilized the largest database of human cancer mutations-TCGA PanCanAtlas, multiple established
Conceptual and theoretical issues are increasingly highlighted in research on international migration.This article looks at some recent developments within feminist mat geography and questions whether feminist theories can contribute to the understanding of international migration.Three main traditions are identified within feminist geography found
Problem.The increase in the level of motorization and in the concentration of vehicles in major cities over the past decade has led to an intensive increase in traffic on the main streets of Ukrainian cities and, as a result, Candle the number of involuntary stops has increased, the speed of traffic flows has decreased, resulting in a cut of the tr
Zoonotic infections are an imminent threat to human health.Pangolins were recently identified as carriers and intermediate hosts of coronaviruses.Previous research has shown that infection with coronaviruses activates an innate immune response upon sensing of viral RNA by interferon-induced with helicase C domain 1 (IFIH1), also known as MDA5.Here,
Mediation analysis is one of the most widely used statistical techniques in the social, behavioral, and medical sciences.Mediation models allow to study how an independent variable affects a dependent variable indirectly through one or more intervening variables, which are called mediators.The analysis is often carried out via a series of linear re